Clinical and haematological evaluation of Pancytopenia : A cross sectional study in a tertiary care centre of Western Odisha

Abstract

Background: Pancytopenia is the outcome of bone marrow abnormalities and progresses with thrombocytopenia, leukopenia, and anemia. The frequently reported clinical manifestations of pancytopenia include infections, hemorrhage, dyspnea, and pallor. This study aimed to improve the diagnostic assessment of pancytopenia by underlying its potential haematological and clinical parameters. 
Materials and Methods: The enrolled patients underwent haematological and clinical assessments for pancytopenia at Veer Surendra Sai Institute of Medical Science and Research, Odisha, India. The pancytopenia assessment parameters included peripheral blood smear, reticulocyte count, mean corpuscular hemoglobin concentration, mean corpuscular hemoglobin, mean corpuscular volume, differential count, total platelet count, total leukocyte count, red blood cell count, and hemoglobin level. Patients also underwent bone marrow aspiration and biopsy for diagnostic investigation.